There are two types of assays available:

  1. SensiScreen® Ready-to-use CE-IVD Assays: SensiScreen® Ready-to-use assays are pre-dispensed in PCR strips and require only addition of patient DNA for somatic mutation testing.
  2. SensiScreen® Dispense Ready CE-IVD Mixes: SensiScreen® Dispense Ready CE-IVD Mixes include all reagents for somatic mutation testing except plastic ware to be used with the real-time PCR system of choice.

Overview of mutations detected by SensiScreen®

SensiScreen® assays detect the most common somatic mutations present in KRAS, NRAS, BRAF and EGFR. Furthermore, a range of new assays is expected to be added to the portfolio in 2017.

BRAF mutations detected by SensiScreen®

Assay CDS mutation Amino acid mutation Cosmic ID
BRAF exon 15 c.1799_1800TG>AT Val600Asp (V600D) COSM477
c.1799T>A Val600Glu (V600E) COSM476
c.1798_1799GT>AA Val600Lys (V600K) COSM473
c.1798_1799GT>AG Val600Arg (V600R) COSM474